Genética, Farmacogenética e Hematologia Molecular

Linhas de pesquisa com interface com a REFARGEN:

• Farmacogenética em leucemia e linfomas
• Utilização de nanoemulsões lipídicas como veículos para terapia gênica/li>
• Células-tronco: Diferenciação, proliferação e morte celular

Publicações selecionadas

1. de Lara Janz F, Favero GM, Bohatch MS Jr, Aguiar Debes A, Bydlowski SP. Simvastatin induces osteogenic differentiation in human amniotic fluid mesenchymal stem cells (AFMSC). Fundam Clin Pharmacol. 2012 Oct 24. doi: 10.1111/fcp.12006. [Epub ahead of print] PubMed PMID: 23094676.
2. Sekiya EJ, Forte A, Kühn TI, Janz F, Bydlowski SP, Alves A. Establishing a stem cell culture laboratory for clinical trials. Rev Bras Hematol Hemoter. 2012;34(3):236-41. doi: 10.5581/1516-8484.20120057. PubMed PMID: 23049427; PubMed Central PMCID: PMC3459639.
3. Santana AC, Dellê H, Cavaglieri RC, Lopes MA, Francisco RP, Zugaib M, Bydlowski SP, Noronha IL. Protective effects of human amniotic fluid stem cells in a model of aorta allograft vasculopathy in rats. Transplant Proc. 2012 Oct;44(8):2490-4. doi: 10.1016/j.transproceed.2012.07.022. PubMed PMID: 23026627.
4. Klionsky DJ e cols , Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 2012 Apr;8(4):445-544. PubMed PMID: 22966490; PubMed Central PMCID: PMC3404883.
5. Levy D, Bellesso M, Oliveira-Souza P, Maciel FV, Pereira J, Bydlowski SP. The H/R FcγRIIA-131 polymorphism and survival in patients with diffuse large B-cell lymphoma (DLBCL) treated with R-CHOP: a study in a genetically mixed population. Clinics (Sao Paulo). 2011;66(5):919-22. PubMed PMID: 21789402; PubMed Central PMCID: PMC3109397.
6. Janz Fde L, Debes Ade A, Cavaglieri Rde C, Duarte SA, Romão CM, Morón AF, Zugaib M, Bydlowski SP. Evaluation of distinct freezing methods and cryoprotectants for human amniotic fluid stem cells cryopreservation. J Biomed Biotechnol. 2012;2012:649353. doi: 10.1155/2012/649353. Epub 2012 May 14. PubMed PMID: 22665987; PubMed Central PMCID: PMC3361720.
7. Favero GM, F Otuki M, Oliveira KA, Bohatch MS Jr, Borelli P, Barros FE, Maria DA, Fernandes D, Bydlowski SP. Simvastatin impairs murine melanoma growth. Lipids Health Dis. 2010 Dec 16;9:142. doi: 10.1186/1476-511X-9-142. PubMed PMID: 21162733; PubMed Central PMCID: PMC3012033.
8. Pereira J, Levy D, Ruiz JL, Brocardo GA, Ferreira KA, Costa RO, Queiroz RG, Maria DA, Neto AE, Chamone DA, Bydlowski SP. Azidothymidine is Effective Against Human Multiple Myeloma: A New Use for an Old Drug? Anticancer Agents Med Chem. 2013 Jan 1;13(1):186-92. PubMed PMID: 22931421.