Farmacologia Clínica e Assistência Farmacêutica

Linhas de pesquisa com interface com a REFARGEN

• Farmacologia clínica
• Farmacogenética do câncer de mama

Publicações selecionadas

1. Vianna-Jorge R, Festa-Vasconcellos JS, Goulart-Citrangulo SM, Leite MS.Functional polymorphisms in xenobiotic metabolizing enzymes and their impact on the therapy of breast cancer. Front Genet. 2012;3:329. doi:10.3389/fgene.2012.00329. Epub 2013 Jan 22. PubMed PMID: 23346096; PubMed Central PMCID: PMC3551254.
2. Festa-Vasconcellos JS, Piranda DN, Amaral LM, Indio-do-Brasil V, Koifman S,Vianna-Jorge R. Polymorphisms in cycloxygenase-2 gene and breast cancer prognosis: association between PTGS2 haplotypes and histopathological features.Breast Cancer Res Treat. 2012 Feb;132(1):251-8. doi: 10.1007/s10549-011-1828-0.Epub 2011 Oct 30. PubMed PMID: 22037828.
3. Piranda DN, Festa-Vasconcellos JS, Amaral LM, Bergmann A, Vianna-Jorge R.Polymorphisms in regulatory regions of cyclooxygenase-2 gene and breast cancer risk in Brazilians: a case-control study. BMC Cancer. 2010 Nov 8;10:613. doi:10.1186/1471-2407-10-613. PubMed PMID: 21059239; PubMed Central PMCID:PMC2992523.
4. Lima MV, Ribeiro GS, Mesquita ET, Victer PR, Vianna-Jorge R. CYP2C9 genotypes and the quality of anticoagulation control with warfarin therapy among Brazilian patients. Eur J Clin Pharmacol. 2008 Jan;64(1):9-15. Epub 2007 Oct 23. PubMed PMID: 17955230.
5. Perini JA, Vianna-Jorge R, Brogliato AR, Suarez-Kurtz G. Influence of CYP2C9 genotypes on the pharmacokinetics and pharmacodynamics of piroxicam. Clin Pharmacol Ther. 2005 Oct;78(4):362-9. PubMed PMID: 16198655.
6. Suarez-Kurtz G, Vianna-Jorge R, Perini JA, Pena SD. Detection of CYP2C9*5 in a white Brazilian subject. Clin Pharmacol Ther. 2005 Jun;77(6):587-8. PubMed PMID:15961990.
7. dos Reis EO, Vianna-Jorge R, Suarez-Kurtz G, Lima EL, Azevedo Dde A.Development of a rapid and specific assay for detection of busulfan in human plasma by high-performance liquid chromatography/electrospray ionization tandem mass spectrometry. Rapid Commun Mass Spectrom. 2005;19(12):1666-74. PubMed PMID:15912469.
8. Vianna-Jorge R, Perini JA, Rondinelli E, Suarez-Kurtz G. CYP2C9 genotypes and the pharmacokinetics of tenoxicam in Brazilians. Clin Pharmacol Ther. 2004 Jul;76(1):18-26. PubMed PMID: 15229460.