Imunogenética

Linhas de pesquisa com interface com a REFARGEN

• Genética de Populações e Microevolução Humana
• Genética e Genômica de Doenças Multifatoriais

Publicações selecionadas

1. Augusto DG, Lobo-Alves SC, Melo MF, Pereira NF, Petzl-Erler ML. Activating KIR and HLA Bw4 ligands are associated to decreased susceptibility to pemphigus foliaceus, an autoimmune blistering skin disease. PLoS One. 2012;7(7):e39991.doi: 10.1371/journal.pone.0039991. Epub 2012 Jul 2. PubMed PMID: 22768326; PubMed Central PMCID: PMC3388041.
2. de Almeida ER, Petzl-Erler ML. Expression of genes involved in susceptibility to multifactorial autoimmune diseases: estimating genotype effects. Int J Immunogenet. 2012 Aug 28. doi: 10.1111/j.1744-313X.2012.01152.x. [Epub ahead of print] PubMed PMID: 22928528.
3. Beltrame MH, Pincerati MR, Dalla-Costa R, Wassem R, Köhler KF,Chautard-Freire-Maia EA, Tsuneto LT, Petzl-Erler ML. CD80 and CD86 polymorphisms in populations of various ancestries: 5 new CD80 promoter alleles. Hum Immunol. 2012 Jan;73(1):111-7. doi: 10.1016/j.humimm.2011.10.018. Epub 2011 Oct 23. PubMed PMID: 22074996.
4. Augusto DG, Zehnder-Alves L, Pincerati MR, Martin MP, Carrington M, Petzl-Erler ML. Diversity of the KIR gene cluster in an urban Brazilian population. Immunogenetics. 2012 Feb;64(2):143-52. doi:10.1007/s00251-011-0565-1. Epub 2011 Aug 18. PubMed PMID: 21850526.
5. Boldt AB, Messias-Reason IJ, Meyer D, Schrago CG, Lang F, Lell B, Dietz K, Kremsner PG, Petzl-Erler ML, Kun JF. Phylogenetic nomenclature and evolution of mannose-binding lectin (MBL2) haplotypes. BMC Genet. 2010 May 14;11:38. doi:10.1186/1471-2156-11-38. PubMed PMID: 20465856; PubMed Central PMCID: PMC2885306.
6. Malheiros D, Petzl-Erler ML. Individual and epistatic effects of genetic polymorphisms of B-cell co-stimulatory molecules on susceptibility to pemphigus foliaceus. Genes Immun. 2009 Sep;10(6):547-58. doi: 10.1038/gene.2009.36. Epub 2009 May 7. PubMed PMID:19421221.
7. Oliveira LA, Ribas F, Bicalho MG, Tsuneto LT, Petzl-Erler ML. High frequencies of alleles MICA*020 and MICA*027 in Amerindians and evidence of positive selection on exon 3. Genes Immun. 2008 Dec;9(8):697-705. doi:10.1038/gene.2008.65. Epub 2008 Sep 11. PubMed PMID: 18784732.
8. Boldt AB, Culpi L, Tsuneto LT, de Souza IR, Kun JF, Petzl-Erler ML. Diversity of the MBL2 gene in various Brazilian populations and the case of selection at the mannose-binding lectin locus. Hum Immunol. 2006 Sep;67(9):722-34. Epub 2006 Jul 10. PubMed PMID: 17002903.
9. Pereira NF, Hansen JA, Lin MT, Roxo VM, Braun K, Petzl-Erler ML. Cytokine gene polymorphisms in endemic pemphigus foliaceus: a possible role for IL6 variants. Cytokine. 2004 Dec 21;28(6):233-41. PubMed PMID: 15566952.
10. Tsuneto LT, Probst CM, Hutz MH, Salzano FM, Rodriguez-Delfin LA, Zago MA, Hill K, Hurtado AM, Ribeiro-dos-Santos AK, Petzl-Erler ML. HLA class II diversity in seven Amerindian populations. Clues about the origins of the Aché. Tissue Antigens. 2003 Dec;62(6):512-26. PubMed PMID: 14617035.