Genômica Médica & Bioinformática

Linhas de pesquisa com interface com a REFARGEN:

• Genômica aplicada a doenças humanas

Publicações selecionadas

1. Tavares R, Renaud G, Oliveira PS, Ferreira CG, Dias-Neto E, Passetti F. Identical sequence patterns in the ends of exons and introns of human protein-coding genes. Comput Biol Chem. 2012 Feb;36:55-61. doi: 10.1016/j.compbiolchem.2012.01.002. Epub 2012 Jan 12. PubMed PMID: 22301201.
2. Staquicini FI, Cardó-Vila M, Kolonin MG, Trepel M, Edwards JK, Nunes DN, Sergeeva A, Efstathiou E, Sun J, Almeida NF, Tu SM, Botz GH, Wallace MJ, O'Connell DJ, Krajewski S, Gershenwald JE, Molldrem JJ, Flamm AL, Koivunen E, Pentz RD, Dias-Neto E, Setubal JC, Cahill DJ, Troncoso P, Do KA, Logothetis CJ, Sidman RL, Pasqualini R, Arap W. Vascular ligand-receptor mapping by direct combinatorial selection in cancer patients. Proc Natl Acad Sci U S A. 2011 Nov 15;108(46):18637-42. doi: 10.1073/pnas.1114503108. Epub 2011 Nov 2. PubMed PMID: 22049339; PubMed Central PMCID: PMC3219136.
3. Carraro DM, Ferreira EN, de Campos Molina G, Puga RD, Abrantes EF, Trapé AP, Eckhardt BL, Nunes DN, Brentani MM, Arap W, Pasqualini R, Brentani H, Dias-Neto E, Brentani RR. Poly (A)+ transcriptome assessment of ERBB2-induced alterations in breast cell lines. PLoS One. 2011;6(6):e21022. doi: 10.1371/journal.pone.0021022. Epub 2011 Jun 22. Erratum in: PLoS One. 2011;6(7). doi:10.1371/annotation/b8888ae6-e402-43af-a425-6fd5e58deef6. Ekhardt, Bedrich L [corrected to Eckhardt, Bedrich L]. PubMed PMID: 21731642; PubMed Central PMCID: PMC3120832.
4. Leschziner GD, Coffey AJ, Andrew T, Gregorio SP, Dias-Neto E, Calafato M, Bentley DR, Kinton L, Sander JW, Johnson MR. Q8IYL2 is a candidate gene for the familial epilepsy syndrome of Partial Epilepsy with Pericentral Spikes (PEPS). Epilepsy Res. 2011 Sep;96(1-2):109-15. doi: 10.1016/j.eplepsyres. 011.05.010. Epub 2011 Jun 11. PubMed PMID: 21658913.
5. Martins-De-Souza D, Dias-Neto E, Schmitt A, Falkai P, Gormanns P, Maccarrone G, Turck CW, Gattaz WF. Proteome analysis of schizophrenia brain tissue. World J Biol Psychiatry. 2010 Mar;11(2):110-20. doi: 10.3109/15622970903490626. Review. PubMed PMID: 20109112.
6. Dias-Neto E, Nunes DN, Giordano RJ, Sun J, Botz GH, Yang K, Setubal JC, Pasqualini R, Arap W. Next-generation phage display: integrating and comparing available molecular tools to enable cost-effective high-throughput analysis. PLoS One. 2009 Dec 17;4(12):e8338. doi: 10.1371/journal.pone.0008338. PubMed PMID: 20020040; PubMed Central PMCID: PMC2791209.
7. Almeida CR, Stoco PH, Wagner G, Sincero TC, Rotava G, Bayer-Santos E, Rodrigues JB, Sperandio MM, Maia AA, Ojopi EP, Zaha A, Ferreira HB, Tyler KM, Dávila AM, Grisard EC, Dias-Neto E. Transcriptome analysis of Taenia solium cysticerci using Open Reading Frame ESTs (ORESTES). Parasit Vectors. 2009 Jul 31;2(1):35. doi: 10.1186/1756-3305-2-35. PubMed PMID: 19646239; PubMed Central PMCID: PMC2731055.
8. Martins-de-Souza D, Gattaz WF, Schmitt A, Novello JC, Marangoni S, Turck CW, Dias-Neto E. Proteome analysis of schizophrenia patients Wernicke's area reveals an energy metabolism dysregulation. BMC Psychiatry. 2009 Apr 30;9:17. doi: 10.1186/1471-244X-9-17. PubMed PMID: 19405953; PubMed Central PMCID: PMC2684104.
9. Estrela Rde C, Ribeiro FS, Barroso PF, Tuyama M, Gregório SP, Dias-Neto E, Struchiner CJ, Suarez-Kurtz G. ABCB1 polymorphisms and the concentrations of lopinavir and ritonavir in blood, semen and saliva of HIV-infected men under antiretroviral therapy. Pharmacogenomics. 2009 Feb;10(2):311-8. doi: 10.2217/14622416.10.2.311. PubMed PMID: 19207033.
10. Staquicini FI, Dias-Neto E, Li J, Snyder EY, Sidman RL, Pasqualini R, Arap W. Discovery of a functional protein complex of netrin-4, laminin gamma1 chain, and integrin alpha6beta1 in mouse neural stem cells. Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2903-8. doi: 10.1073/pnas.0813286106. Epub 2009 Feb 4. PubMed PMID: 19193855; PubMed Central PMCID: PMC2635839.